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Hajime Nakamura Selected Research

Reye Syndrome (Reye's Syndrome)

10/2009Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice.
9/2007Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome.
1/2006Impaired fatty acid utilization in thioredoxin binding protein-2 (TBP-2)-deficient mice: a unique animal model of Reye syndrome.

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Hajime Nakamura Research Topics

Disease

15Neoplasms (Cancer)
10/2021 - 03/2002
14Inflammation (Inflammations)
04/2016 - 08/2002
9Infections
11/2022 - 06/2002
7Hyperbilirubinemia
01/2021 - 11/2014
6Hepatitis
02/2021 - 05/2003
6Fibrosis (Cirrhosis)
01/2013 - 12/2000
6Myocarditis (Carditis)
06/2007 - 08/2002
5Stroke (Strokes)
01/2022 - 10/2017
5Ischemic Stroke
01/2022 - 01/2019
5Ischemia
02/2020 - 01/2002
5Hemorrhage
01/2020 - 01/2006
5Lung Injury
10/2007 - 11/2003
5T-Cell Leukemia (Leukemia, T Cell)
10/2007 - 02/2002
4Neoplasm Metastasis (Metastasis)
02/2021 - 11/2002
4Wounds and Injuries (Trauma)
01/2020 - 04/2007
4Infarction (Infarctions)
01/2020 - 02/2004
4Asthma (Bronchial Asthma)
08/2015 - 04/2003
4Reperfusion Injury
12/2014 - 10/2003
4Chest Pain (Chest Pains)
03/2005 - 09/2003
4Muscle Spasticity (Spastic)
02/2004 - 04/2003
3Sarcoma (Soft Tissue Sarcoma)
12/2022 - 01/2019
3Hypoglycemia (Reactive Hypoglycemia)
04/2021 - 10/2009
3Hepatocellular Carcinoma (Hepatoma)
02/2021 - 01/2016
3Aneurysm (Aneurysms)
01/2020 - 12/2015
3Embolic Stroke
12/2019 - 02/2011
3Breast Neoplasms (Breast Cancer)
01/2019 - 11/2002
3Cardiovascular Diseases (Cardiovascular Disease)
10/2017 - 12/2003
3Chronic Obstructive Pulmonary Disease (COPD)
04/2016 - 10/2007
3Ulcer
01/2014 - 03/2002
3Non-alcoholic Fatty Liver Disease
01/2013 - 01/2003
3Hypoxia (Hypoxemia)
01/2012 - 01/2002
3Reye Syndrome (Reye's Syndrome)
10/2009 - 01/2006
3Pneumonia (Pneumonitis)
05/2008 - 06/2002
3Heart Failure
06/2007 - 08/2002
3Heart Diseases (Heart Disease)
06/2007 - 08/2002
3Myocardial Infarction
09/2004 - 09/2003
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2004 - 04/2003
3Cardiotoxicity
12/2003 - 09/2002
2Liposarcoma
12/2022 - 01/2019
2Thrombosis (Thrombus)
01/2022 - 12/2008
2Intracranial Embolism
01/2022 - 01/2019
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2020 - 08/2002
2Cerebral Infarction
12/2019 - 02/2003
2Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
01/2019 - 12/2016
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2017 - 04/2016
2Pathologic Constriction (Stenosis)
10/2017 - 02/2004
2Atherosclerosis
10/2017 - 11/2003
2Acute Lung Injury
04/2016 - 10/2007
2Birth Weight (Birth Weights)
03/2016 - 01/2016
2Kernicterus
09/2015 - 02/2015
2Diabetes Mellitus
05/2015 - 11/2005
2Diabetic Nephropathies (Diabetic Nephropathy)
05/2015 - 06/2007
2Chronic Renal Insufficiency
05/2015 - 12/2014
2Stomach Ulcer (Gastric Ulcer)
01/2014 - 08/2007

Drug/Important Bio-Agent (IBA)

68ThioredoxinsIBA
05/2015 - 01/2002
23Proteins (Proteins, Gene)FDA Link
02/2020 - 08/2002
11AntioxidantsIBA
10/2021 - 06/2002
11CytokinesIBA
04/2016 - 11/2003
8BilirubinIBA
01/2021 - 08/2002
7Biomarkers (Surrogate Marker)IBA
12/2022 - 02/2002
7Reactive Oxygen Species (Oxygen Radicals)IBA
10/2021 - 04/2003
5tributyl phosphate (TBP)IBA
10/2009 - 03/2002
4EnzymesIBA
10/2017 - 08/2002
4Pharmaceutical PreparationsIBA
01/2016 - 03/2002
4Retinaldehyde (Retinal)IBA
11/2012 - 03/2006
4LipopolysaccharidesIBA
12/2010 - 05/2003
4Glucose (Dextrose)FDA LinkGeneric
12/2010 - 11/2005
4human TXNIP proteinIBA
09/2010 - 01/2006
4Thioacetamide (Thioacetamid)IBA
10/2008 - 05/2003
4Messenger RNA (mRNA)IBA
05/2008 - 01/2002
4Bleomycin (Blenoxane)FDA LinkGeneric
10/2007 - 11/2003
4Vitamin EFDA LinkGeneric
05/2004 - 04/2003
4Doxorubicin (Adriamycin)FDA LinkGeneric
12/2003 - 09/2002
3eribulinFDA Link
12/2022 - 01/2019
3NucleotidesIBA
01/2022 - 04/2001
3AntigensIBA
07/2021 - 06/2009
3Biological ProductsIBA
07/2021 - 05/2005
3SteroidsIBA
02/2021 - 12/2000
3AntibodiesIBA
01/2020 - 05/2005
3ChemokinesIBA
04/2016 - 09/2004
3Acetylcysteine (Siran)FDA LinkGeneric
06/2004 - 02/2002
2Tyrosine Kinase InhibitorsIBA
10/2017 - 04/2016
2Indomethacin (Indometacin)FDA LinkGeneric
04/2016 - 08/2007
2VitaminsIBA
04/2016 - 01/2013
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 05/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2012 - 05/2008
2LipidsIBA
12/2010 - 09/2007
2Fatty Acids (Saturated Fatty Acids)IBA
12/2010 - 01/2006

Therapy/Procedure

27Therapeutics
01/2022 - 12/2000
6Thrombectomy
01/2022 - 12/2015
4Stents
10/2017 - 04/2004
3Endovascular Procedures
01/2022 - 07/2013
3Phototherapy (Light Therapy)
01/2021 - 11/2014
3Lasers (Laser)
09/2016 - 04/2007
2Heart-Assist Devices
11/2020 - 12/2019
2Vagus Nerve Stimulation
01/2020 - 01/2020
2Ligation
01/2019 - 07/2009
2Thrombolytic Therapy
01/2019 - 09/2004
2Liver Transplantation
01/2019 - 08/2005
2Oral Administration
01/2014 - 01/2004